Long noncoding RNA ERLR mediates epithelial-mesenchymal transition of retinal pigment epithelial cells and promotes experimental proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is a disease that causes severe blindness and is characterized by the formation of contractile fibrotic subretinal or epiretinal membranes. The epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE) cells is a hallmark of PVR. This work aims...

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Veröffentlicht in:	Cell death and differentiation 2021-08, Vol.28 (8), p.2351-2366
Hauptverfasser:	Yang, Shuai, Li, Hui, Yao, Haipei, Zhang, Yao, Bao, Huiqian, Wu, Liangjing, Zhang, Conghui, Li, Min, Feng, Le, Zhang, Jingfa, Zheng, Zhi, Xu, Guotong, Wang, Fang
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/109 13/89 14/19 14/32 38/32 38/61 38/71 42/34 631/80/79/1902 692/699/375 82/29 82/58 82/80 96 Animals Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Blindness Cell Biology Cell Cycle Analysis Chromatin Contractility Cytoplasm Disease DNA microarrays Epithelial Cells - metabolism Epithelial-Mesenchymal Transition Experiments Fluorescence in situ hybridization Genomes Growth factors Hospitals Humans Immunoprecipitation Life Sciences Medicine Mesenchyme Metastasis Mice Ophthalmology Pathogenesis Polymerase chain reaction Rabbits Reagents Retina Retinal pigment epithelium Retinal Pigment Epithelium - metabolism RNA, Long Noncoding - genetics Stem Cells Transforming growth factor-b1 Vitreoretinopathy, Proliferative - metabolism
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