The GIST of It: A Rare Presentation of Neurofibromatosis Type I

Neurofibromatosis-1 (NF-1) is an autosomal dominant condition characterized by cutaneous pigmentation and tumour formation along nerves in the brain, skin, and other organs. Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours involving the gastrointestinal tract (GI) associated with...

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Veröffentlicht in:	Curēus (Palo Alto, CA) CA), 2021-06, Vol.13 (6)
Hauptverfasser:	Hudgi, Amit R, Azam, Mohammad, Masood, Muaaz, Arshad, Hafiz Muhammad Sharjeel, Yap, John Erikson L
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Sprache:	eng
Schlagworte:	Gastroenterology Internal Medicine
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creator	Hudgi, Amit R Azam, Mohammad Masood, Muaaz Arshad, Hafiz Muhammad Sharjeel Yap, John Erikson L
description	Neurofibromatosis-1 (NF-1) is an autosomal dominant condition characterized by cutaneous pigmentation and tumour formation along nerves in the brain, skin, and other organs. Gastrointestinal stromal tumours (GIST) are rare mesenchymal tumours involving the gastrointestinal tract (GI) associated with NF-1. We present a case of life-threatening GI bleeding from GIST in a patient with NF-1. In NF-1 patients presenting with GI bleeding, GISTs should be part of the differential. Clinicians must have a low threshold for urgent abdominal imaging if endoscopy does not detect the source of GI bleeding.
doi_str_mv	10.7759/cureus.16034
format	Article
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title	The GIST of It: A Rare Presentation of Neurofibromatosis Type I
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