Ventral hippocampus mediates the context-dependence of two-way signaled avoidance in male rats

•Two-way signaled active avoidance is context-dependent.•Ventral hippocampus muscimol prevents the context-dependence of avoidance.•Dorsal hippocampus muscimol does not impact avoidance responding in either context.•Freezing and avoidance compete in new contexts, but muscimol leaves freezing intact....

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