Thyrotropin receptor antibodies and Graves’ orbitopathy

Context and purpose The thyrotropin receptor (TSHR) is the key autoantigen in Graves’ disease (GD) and associated orbitopathy (GO). Antibodies targeting the TSHR (TSHR-Ab) impact the pathogenesis and the course of GO. This review discusses the role and clinical relevance of TSHR-Ab in GO. Methods Re...

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Veröffentlicht in:	Journal of endocrinological investigation 2021-04, Vol.44 (4), p.703-712
Hauptverfasser:	Diana, T., Ponto, K. A., Kahaly, G. J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acuity Adipocytes Antibodies Biological activity Differential diagnosis Endocrinology Fibroblasts Graves' disease Internal Medicine Medicine Medicine & Public Health Metabolic Diseases Optic neuropathy Short Review Thyroid-stimulating hormone Thyroid-stimulating hormone receptors
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