Environmental Air Pollutants Inhaled during Pregnancy Are Associated with Altered Cord Blood Immune Cell Profiles

Air pollution exposure during pregnancy may be a risk factor for altered immune maturation in the offspring. We investigated the association between ambient air pollutants during pregnancy and cell populations in cord blood from babies born to mothers with asthma enrolled in the Breathing for Life T...

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Veröffentlicht in:	International journal of environmental research and public health 2021-07, Vol.18 (14), p.7431
Hauptverfasser:	Martins Costa Gomes, Gabriela, Karmaus, Wilfried, Murphy, Vanessa E., Gibson, Peter G., Percival, Elizabeth, Hansbro, Philip M., Starkey, Malcolm R., Mattes, Joerg, Collison, Adam M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Air pollution Asthma Babies Birth weight Blood Blood cells Carbon monoxide CD4 antigen CD8 antigen Children Chronic illnesses Cord blood Cytotoxicity Dendritic cells Exposure Fetuses Flow cytometry Fluorescence Humidity Immune system Lung diseases Lymphocytes Lymphocytes T Mothers Nitric oxide Nitrogen dioxide Offspring Organic chemicals Particulate emissions Particulate matter Pollutants Pregnancy Principal components analysis Quality control Respiratory diseases Risk analysis Risk factors Statistical analysis Statistical methods Sulfur Sulfur dioxide Womens health
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Zusammenfassung:	Air pollution exposure during pregnancy may be a risk factor for altered immune maturation in the offspring. We investigated the association between ambient air pollutants during pregnancy and cell populations in cord blood from babies born to mothers with asthma enrolled in the Breathing for Life Trial. For each patient (n = 91), daily mean ambient air pollutant levels were extracted during their entire pregnancy for sulfur dioxide (SO2), nitric oxide, nitrogen dioxide, carbon monoxide, ozone, particulate matter
ISSN:	1660-4601 1661-7827 1660-4601
DOI:	10.3390/ijerph18147431