Characterization of Creatine Kinase Levels in Tofacitinib-Treated Patients with Ulcerative Colitis: Results from Clinical Trials

Background Tofacitinib is an oral, small-molecule JAK inhibitor for the treatment of ulcerative colitis (UC). Creatine kinase (CK) levels and CK-related adverse events (AEs) in tofacitinib-treated patients with UC were evaluated. Methods Data were analyzed for three UC cohorts: Induction (phase 2 an...

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Veröffentlicht in:	Digestive diseases and sciences 2021-08, Vol.66 (8), p.2732-2743
Hauptverfasser:	Panaccione, Remo, Isaacs, John D., Chen, Lea Ann, Wang, Wenjin, Marren, Amy, Kwok, Kenneth, Wang, Lisy, Chan, Gary, Su, Chinyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis Biochemistry Clinical trials Creatine kinase Gastroenterology Hepatology Induction therapy Inflammatory bowel disease Mediation Medical colleges Medicine Medicine & Public Health Oncology Original Original Article Psoriasis Rheumatoid arthritis Rheumatoid factor Tofacitinib Transplant Surgery Ulcerative colitis
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