Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3 +, CF3 •, and CF3 – Reactivity

Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3 +, CF3 •, and CF3 – Reactivity

Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3 +OTf–) as a novel trifluoromethylating reagent, which is conveniently accessible in a single step from thianthrene and triflic anhydride. We demonstrate the use of TT-CF3 +OTf– in electrophilic, radical, a...

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Veröffentlicht in:Journal of the American Chemical Society 2021-05, Vol.143 (20), p.7623-7628
Hauptverfasser: Jia, Hao, Häring, Andreas P, Berger, Florian, Zhang, Li, Ritter, Tobias
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Sprache:eng
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Communication
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container_issue 20
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container_title Journal of the American Chemical Society
container_volume 143
creator Jia, Hao
Häring, Andreas P
Berger, Florian
Zhang, Li
Ritter, Tobias
description Here we report the synthesis and application of trifluoromethyl thianthrenium triflate (TT-CF3 +OTf–) as a novel trifluoromethylating reagent, which is conveniently accessible in a single step from thianthrene and triflic anhydride. We demonstrate the use of TT-CF3 +OTf– in electrophilic, radical, and nucleophilic trifluoromethylation reactions.
doi_str_mv 10.1021/jacs.1c02606
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title Trifluoromethyl Thianthrenium Triflate: A Readily Available Trifluoromethylating Reagent with Formal CF3 +, CF3 •, and CF3 – Reactivity
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