A Small Vimentin-Binding Molecule Blocks Cancer Exosome Release and Reduces Cancer Cell Mobility

Vimentin is an intermediate filament protein with diverse roles in health and disease far beyond its structural functions. Exosomes or small extracellular vesicles (sEVs) are key mediators for intercellular communication, contributing to tissue homeostasis and the progression of various diseases, es...

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Veröffentlicht in:	Frontiers in pharmacology 2021-07, Vol.12, p.627394-627394, Article 627394
Hauptverfasser:	Wu, Jianping, Xie, Qian, Liu, Yanjun, Gao, Yanan, Qu, Zhipeng, Mo, Lian, Xu, Ying, Chen, Ruihuan, Shi, Liyun
Format:	Artikel
Sprache:	eng
Schlagworte:	cancer mobility exosomes inhibitor Life Sciences & Biomedicine Pharmacology Pharmacology & Pharmacy Science & Technology small molecule vimentin
Online-Zugang:	Volltext
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