The Association Pattern between Ambient Temperature Change and Leukocyte Counts
Ambient temperature change is one of the risk factors of human health. Moreover, links between white blood cell counts (WBC) and diseases have been revealed in the literature. Still, we do not know of any association between ambient temperature change and WBC counts. The aim of our study is to inves...
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| Veröffentlicht in: | International journal of environmental research and public health 2021-06, Vol.18 (13), p.6971 |
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| creator | Hung, Shih-Chiang Yang, Chen-Cheng Liu, Chu-Feng Kung, Chia-Te Lee, Wen-Huei Ho, Chi-Kung Chuang, Hung-Yi Yu, Hsin-Su |
| description | Ambient temperature change is one of the risk factors of human health. Moreover, links between white blood cell counts (WBC) and diseases have been revealed in the literature. Still, we do not know of any association between ambient temperature change and WBC counts. The aim of our study is to investigate the relationship between ambient temperature change and WBC counts. We conducted this two-year population-based observational study in Kaohsiung city, recruiting voluntary community participants. Total WBC and differential counts, demographic data and health hazard habits were collected and matched with the meteorological data of air-quality monitoring stations with participants’ study dates and addresses. Generalized additive models (GAM) with penalized smoothing spline functions were performed for the trend of temperature changes and WBC counts. There were 9278 participants (45.3% male, aged 54.3 ± 5.9 years-old) included in analysis. Compared with stable weather conditions, the WBC counts were statistically higher when the one-day lag temperature changed over 2 degrees Celsius, regardless of whether colder or hotter. We found a V-shaped pattern association between WBC counts and temperature changes in GAM. The ambient temperature change was associated with WBC counts, and might imply an impact on systematic inflammation response. |
| doi_str_mv | 10.3390/ijerph18136971 |
| format | Article |
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Moreover, links between white blood cell counts (WBC) and diseases have been revealed in the literature. Still, we do not know of any association between ambient temperature change and WBC counts. The aim of our study is to investigate the relationship between ambient temperature change and WBC counts. We conducted this two-year population-based observational study in Kaohsiung city, recruiting voluntary community participants. Total WBC and differential counts, demographic data and health hazard habits were collected and matched with the meteorological data of air-quality monitoring stations with participants’ study dates and addresses. Generalized additive models (GAM) with penalized smoothing spline functions were performed for the trend of temperature changes and WBC counts. There were 9278 participants (45.3% male, aged 54.3 ± 5.9 years-old) included in analysis. Compared with stable weather conditions, the WBC counts were statistically higher when the one-day lag temperature changed over 2 degrees Celsius, regardless of whether colder or hotter. We found a V-shaped pattern association between WBC counts and temperature changes in GAM. The ambient temperature change was associated with WBC counts, and might imply an impact on systematic inflammation response.</description><identifier>ISSN: 1660-4601</identifier><identifier>ISSN: 1661-7827</identifier><identifier>EISSN: 1660-4601</identifier><identifier>DOI: 10.3390/ijerph18136971</identifier><identifier>PMID: 34209878</identifier><language>eng</language><publisher>Basel: MDPI AG</publisher><subject>Air monitoring ; Air quality ; Alcohol ; Ambient temperature ; Blood ; Disease ; Health hazards ; Health risks ; Hospitals ; Laboratories ; Literature reviews ; Lymphocytes ; Meteorological data ; Morbidity ; Mortality ; Neutrophils ; Population studies ; Risk analysis ; Risk factors ; Spline functions ; Temperature effects ; Weather</subject><ispartof>International journal of environmental research and public health, 2021-06, Vol.18 (13), p.6971</ispartof><rights>2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>2021 by the authors. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c461t-67e30f90fc9f598dc863d08a575356b8b9e3588a44857b704be56ba8a53145fd3</citedby><cites>FETCH-LOGICAL-c461t-67e30f90fc9f598dc863d08a575356b8b9e3588a44857b704be56ba8a53145fd3</cites><orcidid>0000-0001-6658-617X ; 0000-0002-6361-3854 ; 0000-0002-8321-8720</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296857/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8296857/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids></links><search><creatorcontrib>Hung, Shih-Chiang</creatorcontrib><creatorcontrib>Yang, Chen-Cheng</creatorcontrib><creatorcontrib>Liu, Chu-Feng</creatorcontrib><creatorcontrib>Kung, Chia-Te</creatorcontrib><creatorcontrib>Lee, Wen-Huei</creatorcontrib><creatorcontrib>Ho, Chi-Kung</creatorcontrib><creatorcontrib>Chuang, Hung-Yi</creatorcontrib><creatorcontrib>Yu, Hsin-Su</creatorcontrib><title>The Association Pattern between Ambient Temperature Change and Leukocyte Counts</title><title>International journal of environmental research and public health</title><description>Ambient temperature change is one of the risk factors of human health. 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Moreover, links between white blood cell counts (WBC) and diseases have been revealed in the literature. Still, we do not know of any association between ambient temperature change and WBC counts. The aim of our study is to investigate the relationship between ambient temperature change and WBC counts. We conducted this two-year population-based observational study in Kaohsiung city, recruiting voluntary community participants. Total WBC and differential counts, demographic data and health hazard habits were collected and matched with the meteorological data of air-quality monitoring stations with participants’ study dates and addresses. Generalized additive models (GAM) with penalized smoothing spline functions were performed for the trend of temperature changes and WBC counts. There were 9278 participants (45.3% male, aged 54.3 ± 5.9 years-old) included in analysis. Compared with stable weather conditions, the WBC counts were statistically higher when the one-day lag temperature changed over 2 degrees Celsius, regardless of whether colder or hotter. We found a V-shaped pattern association between WBC counts and temperature changes in GAM. The ambient temperature change was associated with WBC counts, and might imply an impact on systematic inflammation response.</abstract><cop>Basel</cop><pub>MDPI AG</pub><pmid>34209878</pmid><doi>10.3390/ijerph18136971</doi><orcidid>https://orcid.org/0000-0001-6658-617X</orcidid><orcidid>https://orcid.org/0000-0002-6361-3854</orcidid><orcidid>https://orcid.org/0000-0002-8321-8720</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Air monitoring Air quality Alcohol Ambient temperature Blood Disease Health hazards Health risks Hospitals Laboratories Literature reviews Lymphocytes Meteorological data Morbidity Mortality Neutrophils Population studies Risk analysis Risk factors Spline functions Temperature effects Weather |
| title | The Association Pattern between Ambient Temperature Change and Leukocyte Counts |
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