Neutrophil recruitment by chemokines Cxcl1/KC and Cxcl2/MIP2: Role of Cxcr2 activation and glycosaminoglycan interactions

Chemokines play a crucial role in combating microbial infection by recruiting blood neutrophils to infected tissue. In mice, the chemokines Cxcl1/KC and Cxcl2/MIP2 fulfill this role. Cxcl1 and Cxcl2 exist as monomers and dimers, and exert their function by activating the Cxcr2 receptor and binding g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of leukocyte biology 2021-04, Vol.109 (4), p.777-791
Hauptverfasser:	Sawant, Kirti V., Sepuru, Krishna Mohan, Lowry, Emily, Penaranda, Brigith, Frevert, Charles W., Garofalo, Roberto P., Rajarathnam, Krishna
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Bone Marrow Cells - cytology CD11b Antigen - metabolism Chemokine CXCL1 - metabolism Chemokine CXCL2 - metabolism Female Glycosaminoglycans - metabolism GPCR inflammation Kinetics leukocyte Mice Mice, Inbred BALB C monomer–dimer Neutrophil Infiltration Peritoneum - cytology Protein Binding Protein Multimerization Protein Transport proteoglycan Receptors, Interleukin-8B - chemistry Receptors, Interleukin-8B - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!