Life-long oligodendrocyte development and plasticity

Oligodendrocyte precursor cells (OPCs) originate in localized germinal zones in the embryonic neural tube, then migrate and proliferate to populate the entire central nervous system, both white and gray matter. They divide and generate myelinating oligodendrocytes (OLs) throughout postnatal and adul...

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Veröffentlicht in:	Seminars in cell & developmental biology 2021-08, Vol.116, p.25-37
Hauptverfasser:	Nishiyama, Akiko, Shimizu, Takahiro, Sherafat, Amin, Richardson, William D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive myelination AMPA receptor Animals Cell Differentiation Humans Learning and memory myelin Neuronal Plasticity - physiology Neurons - metabolism NG2 Oligodendroglia - metabolism PDGF
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