Autoantibodies against p53, MMP-7, and Hsp70 as Potential Biomarkers for Detection of Nonmelanoma Skin Cancers

Basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) are two predominant histological types of nonmelanoma skin cancer (NMSC), lacking effective early diagnostic markers. In this study, we assessed the diagnostic value of autoantibodies against p53, MMP-7, and Hsp70 in skin SCC and BCC. ELIS...

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Veröffentlicht in:	Disease markers 2021, Vol.2021, p.5592693-10
Hauptverfasser:	Yang, Shi-Han, Liu, Can-Tong, Hong, Chao-Qun, Huang, Ze-Yuan, Wang, Huan-Zhu, Wei, Lai-Feng, Lin, Yi-Wei, Guo, Hai-Peng, Peng, Yu-Hui, Xu, Yi-Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens Autoantibodies Autoantibodies - immunology Basal cell carcinoma Biomarkers Biomarkers, Tumor - metabolism Cancer Diagnostic systems Esophagus Female Gene expression HSP70 Heat-Shock Proteins - immunology Hsp70 protein Humans Infant, Newborn Lymphatic system Male Matrilysin Matrix Metalloproteinase 7 - immunology Melanoma Metastasis mRNA p53 Protein Patients Serum levels Skin cancer Skin Neoplasms - diagnosis Squamous cell carcinoma Tumor Suppressor Protein p53 - immunology Tumors
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