The synaptonemal complex central region modulates crossover pathways and feedback control of meiotic double-strand break formation

Abstract The synaptonemal complex (SC) is a proteinaceous structure that mediates homolog engagement and genetic recombination during meiosis. In budding yeast, Zip-Mer-Msh (ZMM) proteins promote crossover (CO) formation and initiate SC formation. During SC elongation, the SUMOylated SC component Ec...

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Veröffentlicht in:	Nucleic acids research 2021-07, Vol.49 (13), p.7537-7553
Hauptverfasser:	Lee, Min-Su, Higashide, Mika T, Choi, Hyungseok, Li, Ke, Hong, Soogil, Lee, Kangseok, Shinohara, Akira, Shinohara, Miki, Kim, Keun P
Format:	Artikel
Sprache:	eng
Schlagworte:	Genome Integrity, Repair and
Online-Zugang:	Volltext
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