Hyperinsulinemia blunts sympathetic vasoconstriction: A possible role of β-adrenergic activation

Herein we report in a sample of healthy young men (n=14) and women (n=12) that hyperinsulinemia induces time-dependent decreases in total peripheral resistance and its contribution to the maintenance of blood pressure. In the same participants, we observe profound vasodilatory effects of insulin in...

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Veröffentlicht in:	American journal of physiology. Regulatory, integrative and comparative physiology integrative and comparative physiology, 2021-06, Vol.320 (6), p.R771-R779
Hauptverfasser:	Limberg, Jaqueline K, Nogueira Soares, Rogerio, Power, Gavin, Harper, Jennifer L, Smith, James A, Shariffi, Brian, Jacob, Dain W, Manrique-Acevedo, Camila M, Padilla, Jaume
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic receptors Aorta Arteries Blood pressure Catecholamine Catecholamines Epinephrine Hyperinsulinemia Insulin Leg Norepinephrine Receptors (physiology) Sympathetic nervous system Vasoconstriction Vasodilation Women
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