Opposite effects of miR-155 in the initial and later stages of lipopolysaccharide (LPS)-induced inflammatory response

Although microRNA-155 (miR-155) is considered a pro-inflammatory mediator, cumulative evidence indicates that it also has anti-inflammatory effects in macrophages and dendritic cells. In this study, we identified the dramatic expression changes of more than half of potential miR-155-targeted genes u...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of Zhejiang University. B. Science 2021-07, Vol.22 (7), p.590-598
Hauptverfasser:	Liu, Yuhua, Wan, Xiaopeng, Yuan, Yuan, Huang, Jingjing, Jiang, Yijia, Zhao, Kaiyue, Wang, Yan, Liu, Yang, Wang, Qingqing, Jin, Hongchuan
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Adaptor Proteins, Signal Transducing - biosynthesis Animals Biomedical and Life Sciences Biomedicine Cytokines Dendritic cells Dendritic Cells - metabolism Endotoxin Tolerance Endotoxins Endotoxins - metabolism Gene regulation Genes Growth factors Immune response Immunity, Innate Immunological tolerance Inflammation Inflammation - metabolism Inflammatory response Innate immunity Kinases Lipopolysaccharides Lipopolysaccharides - metabolism Macrophages Macrophages - metabolism Mice MicroRNAs - genetics MicroRNAs - metabolism miRNA Proteins RAW 264.7 Cells Regulatory mechanisms (biology) Research Article Ribonucleic acid RNA Signal transduction Signal Transduction - drug effects Signaling SOCS-1 protein Suppressor of Cytokine Signaling 1 Protein - biosynthesis TLR4 protein Toll-Like Receptor 4 - biosynthesis Toll-like receptors Transforming growth factor-b
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!