Sirtuin 6 promotes eosinophil differentiation by activating GATA‐1 transcription factor

There is evidence emerging that exposure to cold temperatures enhances alternative activation of macrophages in white adipose tissue (WAT), which promotes adipocyte beiging and adaptive thermogenesis. Although we recently reported that NAD+‐dependent deacetylase sirtuin 6 (Sirt6) drives alternativel...

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Veröffentlicht in:	Aging cell 2021-07, Vol.20 (7), p.e13418-n/a
Hauptverfasser:	Bang, In Hyuk, Park, Dami, Lee, Youngyi, Cho, Hwangeui, Park, Byung‐Hyun, Bae, Eun Ju
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Activating Transcription Factor 1 - metabolism adipocyte beiging Adipose tissue Animals Bone marrow Cell activation Cell culture Cell Differentiation Cytokines eosinophil Eosinophils - metabolism GATA1 Transcription Factor - metabolism GATA‐1 Humans Infiltration Leukocytes (eosinophilic) Lymphocytes T M2 macrophage Macrophages Male Mice NAD Original Original Paper p300 Sirt6 Sirtuins - metabolism Thermogenesis
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