Personalized Proteome: Comparing Proteogenomics and Open Variant Search Approaches for Single Amino Acid Variant Detection

Discovery of variant peptides such as a single amino acid variant (SAAV) in shotgun proteomics data is essential for personalized proteomics. Both the resolution of shotgun proteomics methods and the search engines have improved dramatically, allowing for confident identification of SAAV peptides. H...

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Veröffentlicht in:	Journal of proteome research 2021-06, Vol.20 (6), p.3353-3364
Hauptverfasser:	Salz, Renee, Bouwmeester, Robbin, Gabriels, Ralf, Degroeve, Sven, Martens, Lennart, Volders, Pieter-Jan, ’t Hoen, Peter A.C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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