A primer on emerging field-deployable synthetic biology tools for global water quality monitoring
Tracking progress towards Target 6.1 of the United Nations Sustainable Development Goals, “achieving universal and equitable access to safe and affordable drinking water for all”, necessitates the development of simple, inexpensive tools to monitor water quality. The rapidly growing field of synthet...
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| Veröffentlicht in: | npj clean water 2020-01, Vol.3 (1), Article 18 |
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| creator | Thavarajah, Walter Verosloff, Matthew S. Jung, Jaeyoung K. Alam, Khalid K. Miller, Joshua D. Jewett, Michael C. Young, Sera L. Lucks, Julius B. |
| description | Tracking progress towards Target 6.1 of the United Nations Sustainable Development Goals, “achieving universal and equitable access to safe and affordable drinking water for all”, necessitates the development of simple, inexpensive tools to monitor water quality. The rapidly growing field of synthetic biology has the potential to address this need by isolating DNA-encoded sensing elements from nature and reassembling them to create field-deployable “biosensors” that can detect pathogenic or chemical water contaminants. Here, we describe current water quality monitoring strategies enabled by synthetic biology and compare them to previous approaches used to detect three priority water contaminants (i.e., fecal pathogens, arsenic, and fluoride), as well as explain the potential for engineered biosensors to simplify and decentralize water quality monitoring. We conclude with an outlook on the future of biosensor development, in which we discuss their adaptability to emerging contaminants (e.g., metals, agricultural products, and pharmaceuticals), outline current limitations, and propose steps to overcome the field’s outstanding challenges to facilitate global water quality monitoring. |
| doi_str_mv | 10.1038/s41545-020-0064-8 |
| format | Article |
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| subjects | 704/844/685 706/134 706/2805 Adaptability Agricultural pollution Agricultural products Aquatic Pollution Arsenic Biology Biosensors Chemical pollution Contaminants Deoxyribonucleic acid DNA Drinking water Earth and Environmental Science Environment Environmental monitoring Metals Nanotechnology Pollution monitoring Review Article Sustainable development Synthetic biology Tracking Waste Water Technology Water Industry/Water Technologies Water Management Water pollution Water Pollution Control Water quality Water quality management Water Quality/Water Pollution |
| title | A primer on emerging field-deployable synthetic biology tools for global water quality monitoring |
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