Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans

A diminution in skeletal muscle mitochondrial function due to ectopic lipid accumulation and excess nutrient intake is thought to contribute to insulin resistance and the development of type 2 diabetes. However, the functional integrity of mitochondria in insulin-resistant skeletal muscle remains hi...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2021-08, Vol.121, p.154803-154803, Article 154803
Hauptverfasser:	Axelrod, Christopher L., Fealy, Ciaran E., Erickson, Melissa L., Davuluri, Gangarao, Fujioka, Hisashi, Dantas, Wagner S., Huang, Emily, Pergola, Kathryn, Mey, Jacob T., King, William T., Mulya, Anny, Hsia, Daniel, Burguera, Bartolome, Tandler, Bernard, Hoppel, Charles L., Kirwan, John P.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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