Quantification of Myocardial Creatine and Triglyceride Content in the Human Heart: Precision and Accuracy of in vivo Proton Magnetic Resonance Spectroscopy

Background Proton magnetic resonance spectroscopy (1H‐MRS) of the human heart is deemed to be a quantitative method to investigate myocardial metabolite content, but thorough validations of in vivo measurements against invasive techniques are lacking. Purpose To determine measurement precision and a...

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Veröffentlicht in:	Journal of magnetic resonance imaging 2021-08, Vol.54 (2), p.411-420
Hauptverfasser:	Bakermans, Adrianus J., Boekholdt, S. Matthijs, Vries, Dylan K., Reckman, Yolan J., Farag, Emile S., Heer, Paul, Uthman, Laween, Denis, Simone W., Zuurbier, Coert J., Houtkooper, Riekelt H., Koolbergen, David R., Kluin, Jolanda, Planken, R. Nils, Lamb, Hildo J., Webb, Andrew G., Strijkers, Gustav J., Beard, Daniel A., Jeneson, Jeroen A.L., Nederveen, Aart J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Accuracy Aorta Aortic valve biopsy Creatine EKG Field strength Heart Heart valves In vivo methods and tests Magnetic resonance imaging Magnetic resonance spectroscopy Metabolites Moisture content myectomy myocardial metabolism Original Research Proton magnetic resonance Quantitative analysis Reproducibility Resonance Spectroscopy Spectrum analysis Statistical analysis Statistical methods Statistical tests Tissues Triglycerides validation Water content
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