RNA sequencing reveals potential interacting networks between the altered transcriptome and ncRNome in the skeletal muscle of diabetic mice

For a global epidemic like Type 2 diabetes mellitus (T2DM), while impaired gene regulation is identified as a primary cause of aberrant cellular physiology; in the past few years, non-coding RNAs (ncRNAs) have emerged as important regulators of cellular metabolism. However, there are no reports of c...

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Veröffentlicht in:	Bioscience reports 2021-07, Vol.41 (7)
Hauptverfasser:	Kesharwani, Devesh, Kumar, Amit, Poojary, Mukta, Scaria, Vinod, Datta, Malabika
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-activated protein kinase Animals Biology Cell Line Deregulation Diabetes Diabetes & Metabolic Disorders Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus - genetics Diabetes Mellitus - metabolism Disease Models, Animal Epigenetics Experiments Forkhead protein Gene Expression Profiling Gene regulation Gene Regulatory Networks Gene sequencing Genes Genomics Glucose Human subjects Insulin Insulin - metabolism Insulin resistance Insulin Resistance - genetics Kinases Male Metabolism Metabolites Mice Mice, Inbred C57BL MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism miRNA Molecular Bases of Health & Disease Muscle, Skeletal - metabolism Muscles Musculoskeletal system Myogenesis Non-coding RNA Physiology Regulatory sequences Ribonucleic acid RNA RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism RNA-Seq Signal Transduction Skeletal muscle Transcriptome Transcriptomes
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