Tangutidines A–C, Three Amphoteric Diterpene Alkaloids from Aconitum tanguticum

Three new diterpene alkaloids, tangutidines A–C ( 1 – 3 ), and four known alkaloids ( 4 – 7 ) were isolated from the whole plant of Aconitum tanguticum , from which amphoteric diterpene alkaloids ( 1 – 3 ) were obtained for the first time. The structures of 1 – 3 were elucidated by detailed interpre...

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Veröffentlicht in:Natural Products and Bioprospecting 2021-08, Vol.11 (4), p.459-464
Hauptverfasser: Li, Hao-Yi, Yan, Bing-Chao, Wei, Li-Xin, Sun, Han-Dong, Puno, Pema-Tenzin
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Sprache:eng
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Zusammenfassung:Three new diterpene alkaloids, tangutidines A–C ( 1 – 3 ), and four known alkaloids ( 4 – 7 ) were isolated from the whole plant of Aconitum tanguticum , from which amphoteric diterpene alkaloids ( 1 – 3 ) were obtained for the first time. The structures of 1 – 3 were elucidated by detailed interpretation of spectroscopic data, including MS and NMR data. All of them were evaluated for their cytotoxic activities. Graphic Abstract
ISSN:2192-2195
2192-2209
DOI:10.1007/s13659-021-00310-3