Effect of midodrine versus placebo on time to vasopressor discontinuation in patients with persistent hypotension in the intensive care unit (MIDAS): an international randomised clinical trial

Purpose ICU discharge is often delayed by a requirement for intravenous vasopressor medications to maintain normotension. We hypothesised that the administration of midodrine, an oral α 1 -adrenergic agonist, as adjunct to standard treatment shortens the duration of intravenous vasopressor requireme...

Ausführliche Beschreibung