Complement System and Potential Therapeutics in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a complex multifactorial disease characterized in its late form by neovascularization (wet type) or geographic atrophy of the retinal pigment epithelium cell layer (dry type). The complement system is an intrinsic component of innate immunity. There has been...

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Veröffentlicht in:	International journal of molecular sciences 2021-07, Vol.22 (13), p.6851
Hauptverfasser:	Park, Young Gun, Park, Yong Soo, Kim, In-Beom
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Atrophy Clinical trials Complement Complement system Epithelium Genes Genotypes Homeostasis Immunosurveillance Inflammation Innate immunity Lipids Macular degeneration Metabolism Oxidative stress Pathogenesis Photoreceptors Retina Retinal pigment epithelium Review Risk factors Vascularization
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