DNA molecular combing-based replication fork directionality profiling

Abstract The replication strategy of metazoan genomes is still unclear, mainly because definitive maps of replication origins are missing. High-throughput methods are based on population average and thus may exclusively identify efficient initiation sites, whereas inefficient origins go undetected....

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Veröffentlicht in:	Nucleic acids research 2021-07, Vol.49 (12), p.e69-e69
Hauptverfasser:	Blin, Marion, Lacroix, Laurent, Petryk, Nataliya, Jaszczyszyn, Yan, Chen, Chun-Long, Hyrien, Olivier, Le Tallec, Benoît
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Chickens DNA DNA Replication Genomics - methods Life Sciences Methods Online Sequence Analysis, DNA Transcription, Genetic
Online-Zugang:	Volltext
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