Cardiomyocyte Deletion of Bmal1 Exacerbates QT- and RR-Interval Prolongation in Scn5a+/ΔKPQ Mice

Circadian rhythms are generated by cell autonomous circadian clocks that perform a ubiquitous cellular time-keeping function and cell type-specific functions important for normal physiology. Studies show inducing the deletion of the core circadian clock transcription factor Bmal1 in adult mouse card...

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Veröffentlicht in:	Frontiers in physiology 2021-06, Vol.12, p.681011-681011, Article 681011
Hauptverfasser:	Schroder, Elizabeth A., Wayland, Jennifer L., Samuels, Kaitlyn M., Shah, Syed F., Burgess, Don E., Seward, Tanya, Elayi, Claude S., Esser, Karyn A., Delisle, Brian P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bmal1 electrophysiology heart ion channel Life Sciences & Biomedicine long QT syndrome Physiology Science & Technology SCN5A
Online-Zugang:	Volltext
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