Prediction of a Potential Mechanism of Intervertebral Disc Degeneration Based on a Novel Competitive Endogenous RNA Network

Low back pain which resulted from intervertebral disc degeneration (IDD) is a common health problem that afflicts people all over the world. Due to the lack of an overall understanding of the molecular interactions involved in IDD, we hope to better understand the pathogenetic mechanisms that drive...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021 (1), p.0-6618834
Hauptverfasser:	Huang, Junshen, Li, Yuxi, Ye, Ziwei, Cheng, Ziying, Huang, Jiajun, Lu, Shixin, Su, Kaihui, Liang, Yuwei, Li, Ming, Huang, Lin
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Axes (reference lines) Back pain Bioinformatics Care and treatment Causes of Cell growth Competition Complications and side effects Computational biology Degeneration Degeneration (Pathology) Degenerative disc disease Diagnosis DNA microarrays Extracellular matrix Gene expression Genetic aspects Hernia Hyaluronic acid Identification and classification Intervertebral discs Intervertebral disk Intervertebral disk displacement Low back pain Metabolism MicroRNA miRNA Molecular interactions mRNA Nucleus pulposus Regulation Risk factors RNA Software Spinal diseases Substance abuse treatment
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