Rare case of gastrointestinal mucormycosis with colonic perforation in an immunocompetent patient with COVID-19
Primary gastrointestinal mucormycosis is a rare disease associated with an increased mortality and is rarely reported in an immunocompetent host. We report the first case of mucormycosis-associated colonic perforation in a COVID-19 patient with a favourable outcome. A 48-year-old healthy male doctor...
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| Veröffentlicht in: | BMJ case reports 2021-07, Vol.14 (7), p.e244096 |
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| description | Primary gastrointestinal mucormycosis is a rare disease associated with an increased mortality and is rarely reported in an immunocompetent host. We report the first case of mucormycosis-associated colonic perforation in a COVID-19 patient with a favourable outcome. A 48-year-old healthy male doctor in home isolation due to COVID-19 was admitted to COVID-19 intensive care unit when his symptoms deteriorated. The patient was put on non-invasive ventilation (NIV) using Bilevel Positive Airway Pressure (BiPAP) and treatment given as per existing hospital protocol. The patient improved clinically, and was discharged on day 10 of admission. Two days later, he presented with acute gastrointestinal symptoms to the emergency department. A diagnosis of perforation peritonitis was made, the patient was stabilised and sigmoid colectomy with descending colon colostomy was done. A diagnosis of gastrointestinal mucormycosis was made and injectable antifungal was started. The patient was discharged after his general conditions improved. |
| doi_str_mv | 10.1136/bcr-2021-244096 |
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We report the first case of mucormycosis-associated colonic perforation in a COVID-19 patient with a favourable outcome. A 48-year-old healthy male doctor in home isolation due to COVID-19 was admitted to COVID-19 intensive care unit when his symptoms deteriorated. The patient was put on non-invasive ventilation (NIV) using Bilevel Positive Airway Pressure (BiPAP) and treatment given as per existing hospital protocol. The patient improved clinically, and was discharged on day 10 of admission. Two days later, he presented with acute gastrointestinal symptoms to the emergency department. A diagnosis of perforation peritonitis was made, the patient was stabilised and sigmoid colectomy with descending colon colostomy was done. A diagnosis of gastrointestinal mucormycosis was made and injectable antifungal was started. The patient was discharged after his general conditions improved.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2021-244096</identifier><identifier>PMID: 34215642</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><subject>Abdomen ; Antifungal agents ; Cardiac arrhythmia ; Case Report ; Case reports ; Colon ; Coronaviruses ; COVID-19 ; Diabetes ; Disease ; Emergency medical care ; Fungal infections ; Gangrene ; Histopathology ; Hospitals ; Hypotension ; Immunocompetence ; Infections ; Inflammatory bowel disease ; Intensive care ; Laboratories ; Medical imaging ; Microscopy ; Pain ; Patients ; Peritonitis ; Postoperative period ; Rare diseases ; Sepsis ; Viral infections ; Vomiting</subject><ispartof>BMJ case reports, 2021-07, Vol.14 (7), p.e244096</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained. https://bmj.com/coronavirus/usage?</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. 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We report the first case of mucormycosis-associated colonic perforation in a COVID-19 patient with a favourable outcome. A 48-year-old healthy male doctor in home isolation due to COVID-19 was admitted to COVID-19 intensive care unit when his symptoms deteriorated. The patient was put on non-invasive ventilation (NIV) using Bilevel Positive Airway Pressure (BiPAP) and treatment given as per existing hospital protocol. The patient improved clinically, and was discharged on day 10 of admission. Two days later, he presented with acute gastrointestinal symptoms to the emergency department. A diagnosis of perforation peritonitis was made, the patient was stabilised and sigmoid colectomy with descending colon colostomy was done. A diagnosis of gastrointestinal mucormycosis was made and injectable antifungal was started. The patient was discharged after his general conditions improved.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><pmid>34215642</pmid><doi>10.1136/bcr-2021-244096</doi><oa>free_for_read</oa></addata></record> |
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| subjects | Abdomen Antifungal agents Cardiac arrhythmia Case Report Case reports Colon Coronaviruses COVID-19 Diabetes Disease Emergency medical care Fungal infections Gangrene Histopathology Hospitals Hypotension Immunocompetence Infections Inflammatory bowel disease Intensive care Laboratories Medical imaging Microscopy Pain Patients Peritonitis Postoperative period Rare diseases Sepsis Viral infections Vomiting |
| title | Rare case of gastrointestinal mucormycosis with colonic perforation in an immunocompetent patient with COVID-19 |
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