One year later: SARS-CoV-2 immune response and vaccination of healthcare workers post-infection

A recent study in this journal reported that prior SARS-CoV-2 infection is protective even in the absence of a detectable humoral immune response.1 Our prospective longitudinal study was designed to measure the changes in the binding and neutralizing antibody titers in seropositive healthcare worker...

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Veröffentlicht in:The Journal of infection 2021-09, Vol.83 (3), p.381-412
Hauptverfasser: Dimeglio, Chloé, Herin, Fabrice, Miedougé, Marcel, Da-Silva, Isabelle, Porcheron, Marion, Martin-Blondel, Guillaume, Soulat, Jean-Marc, Izopet, Jacques
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container_end_page 412
container_issue 3
container_start_page 381
container_title The Journal of infection
container_volume 83
creator Dimeglio, Chloé
Herin, Fabrice
Miedougé, Marcel
Da-Silva, Isabelle
Porcheron, Marion
Martin-Blondel, Guillaume
Soulat, Jean-Marc
Izopet, Jacques
description A recent study in this journal reported that prior SARS-CoV-2 infection is protective even in the absence of a detectable humoral immune response.1 Our prospective longitudinal study was designed to measure the changes in the binding and neutralizing antibody titers in seropositive healthcare workers (HCWs) over a year and the changes in individuals who had and had not been vaccinated. We also assessed the incidence of positive SARS-CoV-2 RNA tests among HCWs who were seropositive for SARS-CoV-2 antibodies and in those who were seronegative.
doi_str_mv 10.1016/j.jinf.2021.06.016
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source MEDLINE; Elsevier ScienceDirect Journals
subjects COVID-19
Health Personnel
Healthcare workers
Humans
Immunity
Immunology
Letter to the Editor
Life Sciences
Neutralizing antibodies
SARS-CoV-2
Vaccination
Vaccinology
title One year later: SARS-CoV-2 immune response and vaccination of healthcare workers post-infection
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