The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways
Early in the coronavirus disease 2019 (COVID-19) pandemic, the CDC recommended collection of a lower respiratory tract (LRT) specimen for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing in addition to the routinely recommended upper respiratory tract (URT) testing in mechanically v...
Gespeichert in:
| Veröffentlicht in: | Infection control and hospital epidemiology 2022-10, Vol.43 (10), p.1482-1484 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1484 |
|---|---|
| container_issue | 10 |
| container_start_page | 1482 |
| container_title | Infection control and hospital epidemiology |
| container_volume | 43 |
| creator | Kitt, Eimear M. Davis, Daniela H. Kerman, Caryn Sammons, Julia S. Handy, Lori K. Gallagher, Elizabeth O’Callaghan, Kevin Harris, Rebecca M. Coffin, Susan E. Bell, Louis M. Chiotos, Kathleen |
| description | Early in the coronavirus disease 2019 (COVID-19) pandemic, the CDC recommended collection of a lower respiratory tract (LRT) specimen for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing in addition to the routinely recommended upper respiratory tract (URT) testing in mechanically ventilated patients. Significant operational challenges were noted at our institution using this approach. In this report, we describe our experience with routine collection of paired URT and LRT sample testing. Our results revealed a high concordance between the 2 sources, and that all children tested for SARS-CoV-2 were appropriately diagnosed with URT testing alone. There was no added benefit to LRT testing. Based on these findings, our institutional approach was therefore adjusted to sample the URT alone for most patients, with LRT sampling reserved for patients with ongoing clinical suspicion for SARS-CoV-2 after a negative URT test. |
| doi_str_mv | 10.1017/ice.2021.222 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8245335</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_ice_2021_222</cupid><sourcerecordid>2524867580</sourcerecordid><originalsourceid>FETCH-LOGICAL-c428t-99811015a6ed932b856da4cba25cd310ccd018deecac75ec41310e3ebc715283</originalsourceid><addsrcrecordid>eNptkl2L1DAUhoMo7rh65w8IeLMLdsxH06Y3wjL4BQuCO4h3IU1OZ7K0TU3SGfqj_I9m2EFZMTcn5Dx5857wIvSakjUltH7nDKwZYXTNGHuCVlSIpqgkL5-iFZFNU0jGf1ygFzHeE0LqpqHP0QXnTZVXuUK_tnvAc3K9Swv2HZ60C2DxPE0QsB4t7v0x7wLEyQWdfFhwCtokHPUw9W7c4c4HHOEAAbA2c4JHbFxGG_wA2PjgR31wYY6Y4au7m293xcZ_L9g1ThDTSciN-fXkYEwRH13aYx2S65xxusfZ1VEv8SV61uk-wqtzvUTbjx-2m8_F7ddPXzY3t4UpmUxF00ia_0boCmzDWStFZXVpWs2EsZwSYyyh0gIYbWoBpqT5EDi0pqaCSX6J3j_ITnM7gDXZUtC9moIbdFiU10497oxur3b-oCQrBeciC1ydBYL_Oef51OCigb7XI_g5KiZYKataSJLRN_-g934OY55OsQwISiteZurtA2WCjzFA98cMJeoUA5VjoE4xUDkGGV-fcT20wdkd_FX974XfcgK33g</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2758511634</pqid></control><display><type>article</type><title>The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways</title><source>ProQuest Central</source><source>Cambridge University Press Journals Complete</source><creator>Kitt, Eimear M. ; Davis, Daniela H. ; Kerman, Caryn ; Sammons, Julia S. ; Handy, Lori K. ; Gallagher, Elizabeth ; O’Callaghan, Kevin ; Harris, Rebecca M. ; Coffin, Susan E. ; Bell, Louis M. ; Chiotos, Kathleen</creator><creatorcontrib>Kitt, Eimear M. ; Davis, Daniela H. ; Kerman, Caryn ; Sammons, Julia S. ; Handy, Lori K. ; Gallagher, Elizabeth ; O’Callaghan, Kevin ; Harris, Rebecca M. ; Coffin, Susan E. ; Bell, Louis M. ; Chiotos, Kathleen</creatorcontrib><description>Early in the coronavirus disease 2019 (COVID-19) pandemic, the CDC recommended collection of a lower respiratory tract (LRT) specimen for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing in addition to the routinely recommended upper respiratory tract (URT) testing in mechanically ventilated patients. Significant operational challenges were noted at our institution using this approach. In this report, we describe our experience with routine collection of paired URT and LRT sample testing. Our results revealed a high concordance between the 2 sources, and that all children tested for SARS-CoV-2 were appropriately diagnosed with URT testing alone. There was no added benefit to LRT testing. Based on these findings, our institutional approach was therefore adjusted to sample the URT alone for most patients, with LRT sampling reserved for patients with ongoing clinical suspicion for SARS-CoV-2 after a negative URT test.</description><identifier>ISSN: 0899-823X</identifier><identifier>EISSN: 1559-6834</identifier><identifier>DOI: 10.1017/ice.2021.222</identifier><identifier>PMID: 33966664</identifier><language>eng</language><publisher>New York, USA: Cambridge University Press</publisher><subject>Concise Communication ; Coronaviruses ; COVID-19 ; Ostomy ; Pandemics ; Pediatrics ; Respiratory tract ; Sample size ; Severe acute respiratory syndrome coronavirus 2 ; Software ; Tracheotomy</subject><ispartof>Infection control and hospital epidemiology, 2022-10, Vol.43 (10), p.1482-1484</ispartof><rights>The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America</rights><rights>The Society for Healthcare Epidemiology of America 2021 2021 The Society for Healthcare Epidemiology of America</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c428t-99811015a6ed932b856da4cba25cd310ccd018deecac75ec41310e3ebc715283</citedby><cites>FETCH-LOGICAL-c428t-99811015a6ed932b856da4cba25cd310ccd018deecac75ec41310e3ebc715283</cites><orcidid>0000-0003-0142-2726</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2758511634/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2758511634?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>164,230,314,776,780,881,21367,27901,27902,33721,33722,43781,55603,74273</link.rule.ids></links><search><creatorcontrib>Kitt, Eimear M.</creatorcontrib><creatorcontrib>Davis, Daniela H.</creatorcontrib><creatorcontrib>Kerman, Caryn</creatorcontrib><creatorcontrib>Sammons, Julia S.</creatorcontrib><creatorcontrib>Handy, Lori K.</creatorcontrib><creatorcontrib>Gallagher, Elizabeth</creatorcontrib><creatorcontrib>O’Callaghan, Kevin</creatorcontrib><creatorcontrib>Harris, Rebecca M.</creatorcontrib><creatorcontrib>Coffin, Susan E.</creatorcontrib><creatorcontrib>Bell, Louis M.</creatorcontrib><creatorcontrib>Chiotos, Kathleen</creatorcontrib><title>The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways</title><title>Infection control and hospital epidemiology</title><addtitle>Infect. Control Hosp. Epidemiol</addtitle><description>Early in the coronavirus disease 2019 (COVID-19) pandemic, the CDC recommended collection of a lower respiratory tract (LRT) specimen for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing in addition to the routinely recommended upper respiratory tract (URT) testing in mechanically ventilated patients. Significant operational challenges were noted at our institution using this approach. In this report, we describe our experience with routine collection of paired URT and LRT sample testing. Our results revealed a high concordance between the 2 sources, and that all children tested for SARS-CoV-2 were appropriately diagnosed with URT testing alone. There was no added benefit to LRT testing. Based on these findings, our institutional approach was therefore adjusted to sample the URT alone for most patients, with LRT sampling reserved for patients with ongoing clinical suspicion for SARS-CoV-2 after a negative URT test.</description><subject>Concise Communication</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>Ostomy</subject><subject>Pandemics</subject><subject>Pediatrics</subject><subject>Respiratory tract</subject><subject>Sample size</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Software</subject><subject>Tracheotomy</subject><issn>0899-823X</issn><issn>1559-6834</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNptkl2L1DAUhoMo7rh65w8IeLMLdsxH06Y3wjL4BQuCO4h3IU1OZ7K0TU3SGfqj_I9m2EFZMTcn5Dx5857wIvSakjUltH7nDKwZYXTNGHuCVlSIpqgkL5-iFZFNU0jGf1ygFzHeE0LqpqHP0QXnTZVXuUK_tnvAc3K9Swv2HZ60C2DxPE0QsB4t7v0x7wLEyQWdfFhwCtokHPUw9W7c4c4HHOEAAbA2c4JHbFxGG_wA2PjgR31wYY6Y4au7m293xcZ_L9g1ThDTSciN-fXkYEwRH13aYx2S65xxusfZ1VEv8SV61uk-wqtzvUTbjx-2m8_F7ddPXzY3t4UpmUxF00ia_0boCmzDWStFZXVpWs2EsZwSYyyh0gIYbWoBpqT5EDi0pqaCSX6J3j_ITnM7gDXZUtC9moIbdFiU10497oxur3b-oCQrBeciC1ydBYL_Oef51OCigb7XI_g5KiZYKataSJLRN_-g934OY55OsQwISiteZurtA2WCjzFA98cMJeoUA5VjoE4xUDkGGV-fcT20wdkd_FX974XfcgK33g</recordid><startdate>20221001</startdate><enddate>20221001</enddate><creator>Kitt, Eimear M.</creator><creator>Davis, Daniela H.</creator><creator>Kerman, Caryn</creator><creator>Sammons, Julia S.</creator><creator>Handy, Lori K.</creator><creator>Gallagher, Elizabeth</creator><creator>O’Callaghan, Kevin</creator><creator>Harris, Rebecca M.</creator><creator>Coffin, Susan E.</creator><creator>Bell, Louis M.</creator><creator>Chiotos, Kathleen</creator><general>Cambridge University Press</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>S0X</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-0142-2726</orcidid></search><sort><creationdate>20221001</creationdate><title>The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways</title><author>Kitt, Eimear M. ; Davis, Daniela H. ; Kerman, Caryn ; Sammons, Julia S. ; Handy, Lori K. ; Gallagher, Elizabeth ; O’Callaghan, Kevin ; Harris, Rebecca M. ; Coffin, Susan E. ; Bell, Louis M. ; Chiotos, Kathleen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c428t-99811015a6ed932b856da4cba25cd310ccd018deecac75ec41310e3ebc715283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Concise Communication</topic><topic>Coronaviruses</topic><topic>COVID-19</topic><topic>Ostomy</topic><topic>Pandemics</topic><topic>Pediatrics</topic><topic>Respiratory tract</topic><topic>Sample size</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Software</topic><topic>Tracheotomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kitt, Eimear M.</creatorcontrib><creatorcontrib>Davis, Daniela H.</creatorcontrib><creatorcontrib>Kerman, Caryn</creatorcontrib><creatorcontrib>Sammons, Julia S.</creatorcontrib><creatorcontrib>Handy, Lori K.</creatorcontrib><creatorcontrib>Gallagher, Elizabeth</creatorcontrib><creatorcontrib>O’Callaghan, Kevin</creatorcontrib><creatorcontrib>Harris, Rebecca M.</creatorcontrib><creatorcontrib>Coffin, Susan E.</creatorcontrib><creatorcontrib>Bell, Louis M.</creatorcontrib><creatorcontrib>Chiotos, Kathleen</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Infection control and hospital epidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kitt, Eimear M.</au><au>Davis, Daniela H.</au><au>Kerman, Caryn</au><au>Sammons, Julia S.</au><au>Handy, Lori K.</au><au>Gallagher, Elizabeth</au><au>O’Callaghan, Kevin</au><au>Harris, Rebecca M.</au><au>Coffin, Susan E.</au><au>Bell, Louis M.</au><au>Chiotos, Kathleen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways</atitle><jtitle>Infection control and hospital epidemiology</jtitle><addtitle>Infect. Control Hosp. Epidemiol</addtitle><date>2022-10-01</date><risdate>2022</risdate><volume>43</volume><issue>10</issue><spage>1482</spage><epage>1484</epage><pages>1482-1484</pages><issn>0899-823X</issn><eissn>1559-6834</eissn><abstract>Early in the coronavirus disease 2019 (COVID-19) pandemic, the CDC recommended collection of a lower respiratory tract (LRT) specimen for severe acute respiratory coronavirus virus 2 (SARS-CoV-2) testing in addition to the routinely recommended upper respiratory tract (URT) testing in mechanically ventilated patients. Significant operational challenges were noted at our institution using this approach. In this report, we describe our experience with routine collection of paired URT and LRT sample testing. Our results revealed a high concordance between the 2 sources, and that all children tested for SARS-CoV-2 were appropriately diagnosed with URT testing alone. There was no added benefit to LRT testing. Based on these findings, our institutional approach was therefore adjusted to sample the URT alone for most patients, with LRT sampling reserved for patients with ongoing clinical suspicion for SARS-CoV-2 after a negative URT test.</abstract><cop>New York, USA</cop><pub>Cambridge University Press</pub><pmid>33966664</pmid><doi>10.1017/ice.2021.222</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0003-0142-2726</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0899-823X |
| ispartof | Infection control and hospital epidemiology, 2022-10, Vol.43 (10), p.1482-1484 |
| issn | 0899-823X 1559-6834 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8245335 |
| source | ProQuest Central; Cambridge University Press Journals Complete |
| subjects | Concise Communication Coronaviruses COVID-19 Ostomy Pandemics Pediatrics Respiratory tract Sample size Severe acute respiratory syndrome coronavirus 2 Software Tracheotomy |
| title | The utility of paired upper and lower respiratory tract sampling for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing in patients with artificial airways |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T22%3A31%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20utility%20of%20paired%20upper%20and%20lower%20respiratory%20tract%20sampling%20for%20severe%20acute%20respiratory%20syndrome%20coronavirus%202%20(SARS-CoV-2)%20testing%20in%20patients%20with%20artificial%20airways&rft.jtitle=Infection%20control%20and%20hospital%20epidemiology&rft.au=Kitt,%20Eimear%20M.&rft.date=2022-10-01&rft.volume=43&rft.issue=10&rft.spage=1482&rft.epage=1484&rft.pages=1482-1484&rft.issn=0899-823X&rft.eissn=1559-6834&rft_id=info:doi/10.1017/ice.2021.222&rft_dat=%3Cproquest_pubme%3E2524867580%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2758511634&rft_id=info:pmid/33966664&rft_cupid=10_1017_ice_2021_222&rfr_iscdi=true |