Experimental Design and Sample Size Considerations in Longitudinal MRI Based Biomarker Detection for Multiple Sclerosis

Several modeling approaches have been developed to quantify differences in multiple sclerosis (MS) lesion evolution on magnetic resonance imaging (MRI) to identify the effect of treatment on disease progression. These studies have limited clinical applicability due to onerous scan frequency and leng...

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Veröffentlicht in:	Statistical methods in medical research 2020-02, Vol.29 (9), p.2617-2628
Hauptverfasser:	Hu, Menghan, Schindler, Matthew K., Dewey, Blake E., Reich, Daniel S., Shinohara, Russell T., Eloyan, Ani
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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