High-throughput miRNA sequencing of the human placenta: expression throughout gestation

To understand miRNA changes across gestation in healthy human placentae. This is essential before miRNAs can be used as biomarkers or prognostic indicators during pregnancy. Using next-generation sequencing, we characterize the normative human placenta miRNome in first (n = 113) and third trimester...

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Veröffentlicht in:	Epigenomics 2021-07, Vol.13 (13), p.995-1012
Hauptverfasser:	Gonzalez, Tania L, Eisman, Laura E, Joshi, Nikhil V, Flowers, Amy E, Wu, Di, Wang, Yizhou, Santiskulvong, Chintda, Tang, Jie, Buttle, Rae A, Sauro, Erica, Clark, Ekaterina L, DiPentino, Rosemarie, Jefferies, Caroline A, Chan, Jessica L, Lin, Yayu, Zhu, Yazhen, Afshar, Yalda, Tseng, Hsian-Rong, Taylor, Kent, Williams, 3rd, John, Pisarska, Margareta D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers chorionic villi Computational Biology - methods Female Gene Expression Profiling Gene Expression Regulation Gestational Age gestational differences High-Throughput Nucleotide Sequencing human transcriptome Humans Male MicroRNAs - genetics miRNA miRNA atlas miRNome placenta Placenta - metabolism Pregnancy Pregnancy Outcome stable miRNAs Transcriptome uncomplicated pregnancies
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