Molecular insights on ABL kinase activation using tree-based machine learning models and molecular docking

Abelson kinase (c-Abl) is a non-receptor tyrosine kinase involved in several biological processes essential for cell differentiation, migration, proliferation, and survival. This enzyme's activation might be an alternative strategy for treating diseases such as neutropenia induced by chemothera...

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Veröffentlicht in:Molecular diversity 2021-08, Vol.25 (3), p.1301-1314
Hauptverfasser: Fernandes, Philipe Oliveira, Martins, Diego Magno, de Souza Bozzi, Aline, Martins, João Paulo A., de Moraes, Adolfo Henrique, Maltarollo, Vinícius Gonçalves
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Sprache:eng
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