Minor Changes with Large Implications: Modeling Amino Acid Mutations in SARS‐CoV Monoclonal Antibodies (80R and 362) Towards the Design of More Universal Antibodies

The SARS‐CoV‐2 virus is responsible for the COVID‐19 pandemic which continues to impact nearly every person on Earth, having caused over 1.8 million deaths. Two anti‐SARS‐CoV monoclonal antibodies (MAbs) 80R and 362 are known to bind to epitopes on the spike protein receptor‐binding domain (RBD) and...

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Veröffentlicht in:	The FASEB journal 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02150
Hauptverfasser:	Manikkuttiyil, Carol, Abbas, Feza, Abbas, Lyla, Alzamora, Carolina, Hunt, Matthew, Julakanti, Pujita, Likki, Sanjana, Manikkuttiyil, Christo, Schmitt Lavin, Emily, Sikora, Arthur
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry and Molecular Biology
Online-Zugang:	Volltext
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