Human placental-derived stem cell therapy ameliorates experimental necrotizing enterocolitis

Necrotizing enterocolitis (NEC), a life-threatening intestinal disease, is becoming a larger proportionate cause of morbidity and mortality in premature infants. To date, therapeutic options remain elusive. Based on recent cell therapy studies, we investigated the effect of a human placental-derived...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2021-04, Vol.320 (4), p.G658-G674
Hauptverfasser:	Weis, Victoria G, Deal, Anna C, Mekkey, Gehad, Clouse, Cara, Gaffley, Michaela, Whitaker, Emily, Peeler, Cole B, Weis, Jared A, Schwartz, Marshall Z, Atala, Anthony
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Apoptosis Cell Proliferation Cell therapy Cells, Cultured Cytokines - genetics Cytokines - metabolism Disease Models, Animal Enterocolitis Enterocolitis, Necrotizing - genetics Enterocolitis, Necrotizing - metabolism Enterocolitis, Necrotizing - pathology Enterocolitis, Necrotizing - surgery Epithelial cells Epithelium Female Humans Hypoxia Ileum Ileum - metabolism Ileum - pathology Infants Inflammation Inflammation Mediators - metabolism Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestine Juveniles Lipopolysaccharides Morbidity Morphology Necrotizing enterocolitis Paneth cells Paneth Cells - metabolism Paneth Cells - pathology Placenta Placenta - cytology Placenta - transplantation Pregnancy Rats Rats, Sprague-Dawley Receptors, G-Protein-Coupled - metabolism Small intestine Sox9 protein SOX9 Transcription Factor Stem Cell Niche Stem Cell Transplantation Stem cells Wound Healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!