Engineering Genetic Systems for Treating Mitochondrial Diseases

Mitochondria are intracellular energy generators involved in various cellular processes. Therefore, mitochondrial dysfunction often leads to multiple serious diseases, including neurodegenerative and cardiovascular diseases. A better understanding of the underlying mitochondrial dysfunctions of the...

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Veröffentlicht in:	Pharmaceutics 2021-05, Vol.13 (6), p.810, Article 810
Hauptverfasser:	Jang, Yoon-ha, Ahn, Sae Ryun, Shim, Ji-yeon, Lim, Kwang-il
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Alzheimer's disease Ataxia Binding sites Deafness Gene expression gene therapy Genomes heteroplasmy Life Sciences & Biomedicine Mitochondria mitochondrial disease Mitochondrial DNA mitochondrial gene delivery Mutation Pharmacology & Pharmacy Phosphorylation Physiology Proteins Review RNA polymerase Science & Technology
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