Intravitreal injections: past trends and future projections within a UK tertiary hospital
Aims To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United Kingdom. Methods Retrospective data from Moorfields Eye Hospital were collected using the electronic medical record system. Descriptive stat...
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| Veröffentlicht in: | Eye (London) 2022-07, Vol.36 (7), p.1373-1378 |
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| creator | Chopra, Reena Preston, Gabriella C. Keenan, Tiarnan D. L. Mulholland, Pádraig Patel, Praveen J. Balaskas, Konstantinos Hamilton, Robin D. Keane, Pearse A. |
| description | Aims
To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United Kingdom.
Methods
Retrospective data from Moorfields Eye Hospital were collected using the electronic medical record system. Descriptive statistics were used to visualise overall trends. Time series forecasting was used to predict the number of injections that will be administered up to and including the year 2029.
Results
The number of injections has increased nearly 11-fold from 2009 to 2019, with a total of 44,924 injections delivered in 2019. The majority of injections were given for the treatment of neovascular age-related macular degeneration. Aflibercept formed 87% of injections administered in 2019. The number of injections is predicted to continue to increase every year, with nearly 83,000 injections forecasted in the year 2029.
Conclusion
The demand for intravitreal injections has increased substantially over the last decade and is predicted to further increase. Healthcare systems will need to adapt to accommodate the high demand. Other solutions may include longer-acting therapies to reduce the treatment burden. |
| doi_str_mv | 10.1038/s41433-021-01646-3 |
| format | Article |
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To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United Kingdom.
Methods
Retrospective data from Moorfields Eye Hospital were collected using the electronic medical record system. Descriptive statistics were used to visualise overall trends. Time series forecasting was used to predict the number of injections that will be administered up to and including the year 2029.
Results
The number of injections has increased nearly 11-fold from 2009 to 2019, with a total of 44,924 injections delivered in 2019. The majority of injections were given for the treatment of neovascular age-related macular degeneration. Aflibercept formed 87% of injections administered in 2019. The number of injections is predicted to continue to increase every year, with nearly 83,000 injections forecasted in the year 2029.
Conclusion
The demand for intravitreal injections has increased substantially over the last decade and is predicted to further increase. Healthcare systems will need to adapt to accommodate the high demand. Other solutions may include longer-acting therapies to reduce the treatment burden.</description><identifier>ISSN: 0950-222X</identifier><identifier>EISSN: 1476-5454</identifier><identifier>DOI: 10.1038/s41433-021-01646-3</identifier><identifier>PMID: 34172943</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/699/3161/3175 ; 692/700/565/1436 ; Age ; Electronic medical records ; Laboratory Medicine ; Macular degeneration ; Medicine ; Medicine & Public Health ; Ophthalmology ; Pharmaceutical Sciences/Technology ; Surgery ; Surgical Oncology ; Trends</subject><ispartof>Eye (London), 2022-07, Vol.36 (7), p.1373-1378</ispartof><rights>The Author(s) 2021</rights><rights>The Author(s) 2021. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c474t-a5b8cf893f8cb90fb4598628e78dcf7e4fef0859cfc1c187c534d0f4fab879c13</citedby><cites>FETCH-LOGICAL-c474t-a5b8cf893f8cb90fb4598628e78dcf7e4fef0859cfc1c187c534d0f4fab879c13</cites><orcidid>0000-0001-8682-4067 ; 0000-0002-9239-745X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227364/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8227364/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34172943$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chopra, Reena</creatorcontrib><creatorcontrib>Preston, Gabriella C.</creatorcontrib><creatorcontrib>Keenan, Tiarnan D. L.</creatorcontrib><creatorcontrib>Mulholland, Pádraig</creatorcontrib><creatorcontrib>Patel, Praveen J.</creatorcontrib><creatorcontrib>Balaskas, Konstantinos</creatorcontrib><creatorcontrib>Hamilton, Robin D.</creatorcontrib><creatorcontrib>Keane, Pearse A.</creatorcontrib><title>Intravitreal injections: past trends and future projections within a UK tertiary hospital</title><title>Eye (London)</title><addtitle>Eye</addtitle><addtitle>Eye (Lond)</addtitle><description>Aims
To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United Kingdom.
Methods
Retrospective data from Moorfields Eye Hospital were collected using the electronic medical record system. Descriptive statistics were used to visualise overall trends. Time series forecasting was used to predict the number of injections that will be administered up to and including the year 2029.
Results
The number of injections has increased nearly 11-fold from 2009 to 2019, with a total of 44,924 injections delivered in 2019. The majority of injections were given for the treatment of neovascular age-related macular degeneration. Aflibercept formed 87% of injections administered in 2019. The number of injections is predicted to continue to increase every year, with nearly 83,000 injections forecasted in the year 2029.
Conclusion
The demand for intravitreal injections has increased substantially over the last decade and is predicted to further increase. Healthcare systems will need to adapt to accommodate the high demand. Other solutions may include longer-acting therapies to reduce the treatment burden.</description><subject>692/699/3161/3175</subject><subject>692/700/565/1436</subject><subject>Age</subject><subject>Electronic medical records</subject><subject>Laboratory Medicine</subject><subject>Macular degeneration</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ophthalmology</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Trends</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1vFSEYhUmjsdfqH-iiIXHjZpSPdwamiyZN40djEzc20RVhGOjlZi5Mganx30u9_bAuXJHwPu_hHA5Ch5S8o4TL9xkocN4QRhtCO-gavodWFETXtNDCM7QifUsaxtj3ffQy5w0hdSjIC7TPgQrWA1-hH-ehJH3jS7J6wj5srCk-hnyMZ50LrtdhzFiHEbulLMniOcV7Bv_0Ze0D1vjyCy42Fa_TL7yOefZFT6_Qc6enbF_fnQfo8uOHb2efm4uvn87PTi8aAwJKo9tBGid77qQZeuIGaHvZMWmFHI0TFpx1RLa9cYYaKoVpOYzEgdODFL2h_ACd7HTnZdja0djbQJOak99WOypqr55Ogl-rq3ijJGOCd1AF3t4JpHi92FzU1mdjp0kHG5esWP3N6gmIrOibf9BNXFKo8RTrJAFg1Wql2I4yKeacrHswQ4m6bU7tmlO1OfWnOcXr0tHfMR5W7quqAN8BuY7ClU2Pb_9H9jeix6aO</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Chopra, Reena</creator><creator>Preston, Gabriella C.</creator><creator>Keenan, Tiarnan D. L.</creator><creator>Mulholland, Pádraig</creator><creator>Patel, Praveen J.</creator><creator>Balaskas, Konstantinos</creator><creator>Hamilton, Robin D.</creator><creator>Keane, Pearse A.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-8682-4067</orcidid><orcidid>https://orcid.org/0000-0002-9239-745X</orcidid></search><sort><creationdate>20220701</creationdate><title>Intravitreal injections: past trends and future projections within a UK tertiary hospital</title><author>Chopra, Reena ; Preston, Gabriella C. ; Keenan, Tiarnan D. L. ; Mulholland, Pádraig ; Patel, Praveen J. ; Balaskas, Konstantinos ; Hamilton, Robin D. ; Keane, Pearse A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c474t-a5b8cf893f8cb90fb4598628e78dcf7e4fef0859cfc1c187c534d0f4fab879c13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>692/699/3161/3175</topic><topic>692/700/565/1436</topic><topic>Age</topic><topic>Electronic medical records</topic><topic>Laboratory Medicine</topic><topic>Macular degeneration</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ophthalmology</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Trends</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chopra, Reena</creatorcontrib><creatorcontrib>Preston, Gabriella C.</creatorcontrib><creatorcontrib>Keenan, Tiarnan D. L.</creatorcontrib><creatorcontrib>Mulholland, Pádraig</creatorcontrib><creatorcontrib>Patel, Praveen J.</creatorcontrib><creatorcontrib>Balaskas, Konstantinos</creatorcontrib><creatorcontrib>Hamilton, Robin D.</creatorcontrib><creatorcontrib>Keane, Pearse A.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chopra, Reena</au><au>Preston, Gabriella C.</au><au>Keenan, Tiarnan D. L.</au><au>Mulholland, Pádraig</au><au>Patel, Praveen J.</au><au>Balaskas, Konstantinos</au><au>Hamilton, Robin D.</au><au>Keane, Pearse A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intravitreal injections: past trends and future projections within a UK tertiary hospital</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><addtitle>Eye (Lond)</addtitle><date>2022-07-01</date><risdate>2022</risdate><volume>36</volume><issue>7</issue><spage>1373</spage><epage>1378</epage><pages>1373-1378</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><abstract>Aims
To describe past trends and future projections for the number of intravitreal injections being administered at a large tertiary hospital in London, United Kingdom.
Methods
Retrospective data from Moorfields Eye Hospital were collected using the electronic medical record system. Descriptive statistics were used to visualise overall trends. Time series forecasting was used to predict the number of injections that will be administered up to and including the year 2029.
Results
The number of injections has increased nearly 11-fold from 2009 to 2019, with a total of 44,924 injections delivered in 2019. The majority of injections were given for the treatment of neovascular age-related macular degeneration. Aflibercept formed 87% of injections administered in 2019. The number of injections is predicted to continue to increase every year, with nearly 83,000 injections forecasted in the year 2029.
Conclusion
The demand for intravitreal injections has increased substantially over the last decade and is predicted to further increase. Healthcare systems will need to adapt to accommodate the high demand. Other solutions may include longer-acting therapies to reduce the treatment burden.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>34172943</pmid><doi>10.1038/s41433-021-01646-3</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-8682-4067</orcidid><orcidid>https://orcid.org/0000-0002-9239-745X</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Eye (London), 2022-07, Vol.36 (7), p.1373-1378 |
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| source | PubMed Central; Alma/SFX Local Collection |
| subjects | 692/699/3161/3175 692/700/565/1436 Age Electronic medical records Laboratory Medicine Macular degeneration Medicine Medicine & Public Health Ophthalmology Pharmaceutical Sciences/Technology Surgery Surgical Oncology Trends |
| title | Intravitreal injections: past trends and future projections within a UK tertiary hospital |
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