Genetic Predisposition to Alzheimer’s Disease Is Associated with Enlargement of Perivascular Spaces in Centrum Semiovale Region

This study investigated whether genetic factors involved in Alzheimer’s disease (AD) are associated with enlargement of Perivascular Spaces (ePVS) in the brain. A total of 680 participants with T2-weighted MRI scans and genetic information were acquired from the ALFA study. ePVS in the basal ganglia...

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Veröffentlicht in:	Genes 2021-05, Vol.12 (6), p.825
Hauptverfasser:	Ciampa, Iacopo, Operto, Grégory, Falcon, Carles, Minguillon, Carolina, Castro de Moura, Manuel, Piñeyro, David, Esteller, Manel, Molinuevo, Jose, Guigó, Roderic, Navarro, Arcadi, Gispert, Juan, Vilor-Tejedor, Natalia
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Alzheimer's disease Apolipoprotein E Basal ganglia Blood-brain barrier Brain research Enlargement Gene polymorphism Genetic factors Genomes Genotype & phenotype Magnetic resonance imaging Metabolism Neurodegenerative diseases Polymorphism Regression analysis
Online-Zugang:	Volltext
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