Down-regulation of HIV-1 Infection by Inhibition of the MAPK Signaling Pathway

The human immunodeficiency virus type 1 （HIV-1） can interact with and exploit the host cellular machinery to replicate and propagate itself. Numerous studies have shown that the Mitogen-activated protein kinase （MAPK） signal pathway can positively regulate the replication of HIV-1, but exactly how e...

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Veröffentlicht in:	Virologica Sinica 2011-04, Vol.26 (2), p.114-122
Hauptverfasser:	Gong, Jian, Shen, Xi-hui, Chen, Chao, Qiu, Hui, Yang, Rong-ge
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Cell Line Down-Regulation - drug effects HIV HIV Infections - enzymology HIV Infections - virology HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus Human immunodeficiency virus 1 Humans MAP Kinase Signaling System - drug effects MAPK信号通路 Medical Microbiology Microbial Genetics and Genomics Microbiology mitogen-activated protein kinase Mitogen-Activated Protein Kinases - antagonists & inhibitors Mitogen-Activated Protein Kinases - genetics Mitogen-Activated Protein Kinases - metabolism Oncology PD98059 Protein Kinase Inhibitors - pharmacology Virology Virus Replication - drug effects viruses 丝裂原活化蛋白激酶人类免疫缺陷病毒抑制作用细胞外信号调节激酶
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