The American lobster genome reveals insights on longevity, neural, and immune adaptations
The American lobster, , is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuable model for deciphering neural networks controlling rhythmic motor patterns and olfaction. Here, we report a high-quality draft assembly of the genome wi...
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| Veröffentlicht in: | Science advances 2021-06, Vol.7 (26) |
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| creator | Polinski, Jennifer M Zimin, Aleksey V Clark, K Fraser Kohn, Andrea B Sadowski, Norah Timp, Winston Ptitsyn, Andrey Khanna, Prarthana Romanova, Daria Y Williams, Peter Greenwood, Spencer J Moroz, Leonid L Walt, David R Bodnar, Andrea G |
| description | The American lobster,
, is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuable model for deciphering neural networks controlling rhythmic motor patterns and olfaction. Here, we report a high-quality draft assembly of the
genome with 25,284 predicted gene models. Analysis of the neural gene complement revealed extraordinary development of the chemosensory machinery, including a profound diversification of ligand-gated ion channels and secretory molecules. The discovery of a novel class of chimeric receptors coupling pattern recognition and neurotransmitter binding suggests a deep integration between the neural and immune systems. A robust repertoire of genes involved in innate immunity, genome stability, cell survival, chemical defense, and cuticle formation represents a diversity of defense mechanisms essential to thrive in the benthic marine environment. Together, these unique evolutionary adaptations contribute to the longevity and ecological success of this long-lived benthic predator. |
| doi_str_mv | 10.1126/sciadv.abe8290 |
| format | Article |
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, is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuable model for deciphering neural networks controlling rhythmic motor patterns and olfaction. Here, we report a high-quality draft assembly of the
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Together, these unique evolutionary adaptations contribute to the longevity and ecological success of this long-lived benthic predator.</description><subject>Animals</subject><subject>Ecosystem</subject><subject>Genetics</subject><subject>Longevity - genetics</subject><subject>Nephropidae - genetics</subject><subject>Nephropidae - metabolism</subject><subject>Nervous System</subject><subject>Neuroscience</subject><subject>SciAdv r-articles</subject><issn>2375-2548</issn><issn>2375-2548</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkc1rAjEQxUNpqWK99lhy7EFtNsl-XQoi_QKhFy89hWwyqym7iU12Bf_7RrRiTxnIb97MvIfQfUJmSUKzp6CM1LuZrKCgJblCQ8rydEpTXlxf1AM0DuGbEJLwLEuT8hYNGE8ymrJsiL5WG8DzFrxR0uLGVaEDj9dgXQvYww5kE7Cxwaw3XcDugNg17Ey3n2ALvZfNBEursWnb3gKWWm472Rlnwx26qWMzjE_vCK1eX1aL9-ny8-1jMV9OFStJN03zWsVboFYc0lopxVRKK1bxWpVakpJRrWSRFCUvcy1zqhnXeZVqwopCR3qEno-y275qQSuwXVxKbL1ppd8LJ434_2PNRqzdThSURhN4FHg8CXj300PoRGuCgqaRFlwfRLSQFxHO84jOjqjyLgQP9XlMQsQhEXFMRJwSiQ0Pl8ud8T__2S-RwIwN</recordid><startdate>20210601</startdate><enddate>20210601</enddate><creator>Polinski, Jennifer M</creator><creator>Zimin, Aleksey V</creator><creator>Clark, K Fraser</creator><creator>Kohn, Andrea B</creator><creator>Sadowski, Norah</creator><creator>Timp, Winston</creator><creator>Ptitsyn, Andrey</creator><creator>Khanna, Prarthana</creator><creator>Romanova, Daria Y</creator><creator>Williams, Peter</creator><creator>Greenwood, Spencer J</creator><creator>Moroz, Leonid L</creator><creator>Walt, David R</creator><creator>Bodnar, Andrea G</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5091-3092</orcidid><orcidid>https://orcid.org/0000-0002-3841-2807</orcidid><orcidid>https://orcid.org/0000-0003-2083-6027</orcidid><orcidid>https://orcid.org/0000-0002-1333-3176</orcidid><orcidid>https://orcid.org/0000-0003-1196-8757</orcidid><orcidid>https://orcid.org/0000-0002-2982-3161</orcidid><orcidid>https://orcid.org/0000-0002-7508-3969</orcidid><orcidid>https://orcid.org/0000-0002-6611-2780</orcidid><orcidid>https://orcid.org/0000-0002-7864-5445</orcidid><orcidid>https://orcid.org/0000-0003-2594-5070</orcidid><orcidid>https://orcid.org/0000-0002-5524-7348</orcidid></search><sort><creationdate>20210601</creationdate><title>The American lobster genome reveals insights on longevity, neural, and immune adaptations</title><author>Polinski, Jennifer M ; 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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Animals Ecosystem Genetics Longevity - genetics Nephropidae - genetics Nephropidae - metabolism Nervous System Neuroscience SciAdv r-articles |
| title | The American lobster genome reveals insights on longevity, neural, and immune adaptations |
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