Switching Cytolytic Nanopores into Antimicrobial Fractal Ruptures by a Single Side Chain Mutation

Disruption of cell membranes is a fundamental host defense response found in virtually all forms of life. The molecular mechanisms vary but generally lead to energetically favored circular nanopores. Here, we report an elaborate fractal rupture pattern induced by a single side-chain mutation in ultr...

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Veröffentlicht in:	ACS nano 2021-06, Vol.15 (6), p.9679-9689
Hauptverfasser:	Hammond, Katharine, Cipcigan, Flaviu, Al Nahas, Kareem, Losasso, Valeria, Lewis, Helen, Cama, Jehangir, Martelli, Fausto, Simcock, Patrick W, Fletcher, Marcus, Ravi, Jascindra, Stansfeld, Phillip J, Pagliara, Stefano, Hoogenboom, Bart W, Keyser, Ulrich F, Sansom, Mark S. P, Crain, Jason, Ryadnov, Maxim G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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