HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates

A strategy has been established for the synthesis of a family of bifunctional HIV-1 inhibitor covalent conjugates with the potential to bind simultaneously to both the gp120 and gp41 subunits of the HIV-1 envelope glycoprotein trimeric complex (Env). One component of the conjugates is derived from B...

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Veröffentlicht in:	ACS chemical biology 2021-01, Vol.16 (1), p.193-204
Hauptverfasser:	Gaffney, Althea, Nangarlia, Aakansha, Ang, Charles G, Gossert, Steven, Rashad Ahmed, Adel Ahmed, Hossain, Md Alamgir, Abrams, Cameron F, Smith, 3rd, Amos B, Chaiken, Irwin
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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