Compound FC-10696 Inhibits Egress of Marburg Virus

Marburg virus (MARV) VP40 protein (mVP40) directs egress and spread of MARV, in part, by recruiting specific host WW domain-containing proteins via its conserved PPxY late (L) domain motif to facilitate efficient virus-cell separation. We reported previously that small-molecule compounds targeting t...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2021-06, Vol.65 (7), p.e0008621-e0008621
Hauptverfasser:	Han, Ziying, Ye, Hong, Liang, Jingjing, Shepley-McTaggart, Ariel, Wrobel, Jay E, Reitz, Allen B, Whigham, Alison, Kavelish, Katrina N, Saporito, Michael S, Freedman, Bruce D, Shtanko, Olena, Harty, Ronald N
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents HeLa Cells Humans Marburgvirus Mice Virus Release
Online-Zugang:	Volltext
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