Black thyroid: a benign finding
Physical examination revealed a hard stone consistency thyroid nodule fixed to surrounding tissues in the right lobe of approximately 15 mm. Ultrasound revealed a 17×10 mm solid nodule in the right lobe of heterogeneous echogenicity with microcalcifications. Fine-needle aspiration biopsy showed epit...
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description | Physical examination revealed a hard stone consistency thyroid nodule fixed to surrounding tissues in the right lobe of approximately 15 mm. Ultrasound revealed a 17×10 mm solid nodule in the right lobe of heterogeneous echogenicity with microcalcifications. Fine-needle aspiration biopsy showed epithelial cell sheets with increased dense chromatin nuclear volume, clefts, evident nucleolus and haematic background suggestive of malignancy (Bethesda IV). [...]they do not affect the gland’s functionality.3 Black thyroids were also reported in cystic fibrosis and less common in hereditary haemochromatosis and ochronosis.4 5 Thyroid neoplasm has been reported in 65% of patients with black thyroid; nevertheless, the high prevalence of malignancy can be explained by the fact that black thyroid is diagnosed during the thyroid malignancy diagnostic workup triggered by the overdiagnosis of thyroid cancer.6 Neither black thyroid nor minocycline has been associated with an increased risk of malignancy or more aggressive cancer.7 Patient’s perspective When they found a nodule in my thyroid and explained that it could be cancer, I was devastated. |
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Ultrasound revealed a 17×10 mm solid nodule in the right lobe of heterogeneous echogenicity with microcalcifications. Fine-needle aspiration biopsy showed epithelial cell sheets with increased dense chromatin nuclear volume, clefts, evident nucleolus and haematic background suggestive of malignancy (Bethesda IV). [...]they do not affect the gland’s functionality.3 Black thyroids were also reported in cystic fibrosis and less common in hereditary haemochromatosis and ochronosis.4 5 Thyroid neoplasm has been reported in 65% of patients with black thyroid; nevertheless, the high prevalence of malignancy can be explained by the fact that black thyroid is diagnosed during the thyroid malignancy diagnostic workup triggered by the overdiagnosis of thyroid cancer.6 Neither black thyroid nor minocycline has been associated with an increased risk of malignancy or more aggressive cancer.7 Patient’s perspective When they found a nodule in my thyroid and explained that it could be cancer, I was devastated.</description><identifier>ISSN: 1757-790X</identifier><identifier>EISSN: 1757-790X</identifier><identifier>DOI: 10.1136/bcr-2021-242133</identifier><identifier>PMID: 34155017</identifier><language>eng</language><publisher>England: BMJ Publishing Group LTD</publisher><subject>Acne ; Antibiotics ; Asymptomatic ; Case reports ; Cysts ; Humans ; Images In ; Neuroendocrine tumors ; Thyroid cancer ; Thyroid Diseases - diagnosis ; Thyroid Diseases - surgery ; Thyroid Neoplasms - surgery ; Thyroidectomy ; Thyroiditis ; Tumors</subject><ispartof>BMJ case reports, 2021-06, Vol.14 (6), p.e242133</ispartof><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2021 BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ. 2021</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-b410t-c369a9d100616b430d45925be2b66e6f884ccb987a618afdf718dfce02e10a483</cites><orcidid>0000-0002-4410-7059</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217919/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8217919/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27903,27904,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34155017$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Solis-Pazmino, Paola</creatorcontrib><creatorcontrib>Hallo, Alejandro</creatorcontrib><creatorcontrib>Lincango-Naranjo, Eddy</creatorcontrib><creatorcontrib>Garcia, Cristhian</creatorcontrib><title>Black thyroid: a benign finding</title><title>BMJ case reports</title><addtitle>BMJ Case Rep</addtitle><description>Physical examination revealed a hard stone consistency thyroid nodule fixed to surrounding tissues in the right lobe of approximately 15 mm. Ultrasound revealed a 17×10 mm solid nodule in the right lobe of heterogeneous echogenicity with microcalcifications. Fine-needle aspiration biopsy showed epithelial cell sheets with increased dense chromatin nuclear volume, clefts, evident nucleolus and haematic background suggestive of malignancy (Bethesda IV). [...]they do not affect the gland’s functionality.3 Black thyroids were also reported in cystic fibrosis and less common in hereditary haemochromatosis and ochronosis.4 5 Thyroid neoplasm has been reported in 65% of patients with black thyroid; nevertheless, the high prevalence of malignancy can be explained by the fact that black thyroid is diagnosed during the thyroid malignancy diagnostic workup triggered by the overdiagnosis of thyroid cancer.6 Neither black thyroid nor minocycline has been associated with an increased risk of malignancy or more aggressive cancer.7 Patient’s perspective When they found a nodule in my thyroid and explained that it could be cancer, I was devastated.</description><subject>Acne</subject><subject>Antibiotics</subject><subject>Asymptomatic</subject><subject>Case reports</subject><subject>Cysts</subject><subject>Humans</subject><subject>Images In</subject><subject>Neuroendocrine tumors</subject><subject>Thyroid cancer</subject><subject>Thyroid Diseases - diagnosis</subject><subject>Thyroid Diseases - surgery</subject><subject>Thyroid Neoplasms - surgery</subject><subject>Thyroidectomy</subject><subject>Thyroiditis</subject><subject>Tumors</subject><issn>1757-790X</issn><issn>1757-790X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2021</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqFkM1LwzAYh4MobsydvWnBiwjVvEmaJh4EHX7BwIuCt5Ck6dbZj5m2wv57OzrH9OJ7yQt58iO_B6FjwJcAlF8Z60OCCYSEEaB0Dw0hjuIwlvh9f2cfoHFdL3A3FJhg9BANKIMowhAP0eldru1H0MxXvsqS60AHxpXZrAzSrEyycnaEDlKd1268OUfo7eH-dfIUTl8enye309AwwE1oKZdaJoAxB24YxQmLJImMI4Zzx1MhmLVGilhzEDpN0hhEklqHiQOsmaAjdNPnLltTuMS6svE6V0ufFdqvVKUz9fumzOZqVn0pQSCWILuA802Arz5bVzeqyGrr8lyXrmprRSLGgLMIsw49-4MuqtaXXb01RSWNpeAdddVT1ld17V26_QxgtfavOv9q7V_1_rsXJ7sdtvyP7Q646AFTLP5N-wZgc4u7</recordid><startdate>20210621</startdate><enddate>20210621</enddate><creator>Solis-Pazmino, Paola</creator><creator>Hallo, Alejandro</creator><creator>Lincango-Naranjo, Eddy</creator><creator>Garcia, Cristhian</creator><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-4410-7059</orcidid></search><sort><creationdate>20210621</creationdate><title>Black thyroid: a benign finding</title><author>Solis-Pazmino, Paola ; Hallo, Alejandro ; Lincango-Naranjo, Eddy ; Garcia, Cristhian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b410t-c369a9d100616b430d45925be2b66e6f884ccb987a618afdf718dfce02e10a483</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2021</creationdate><topic>Acne</topic><topic>Antibiotics</topic><topic>Asymptomatic</topic><topic>Case reports</topic><topic>Cysts</topic><topic>Humans</topic><topic>Images In</topic><topic>Neuroendocrine tumors</topic><topic>Thyroid cancer</topic><topic>Thyroid Diseases - diagnosis</topic><topic>Thyroid Diseases - surgery</topic><topic>Thyroid Neoplasms - surgery</topic><topic>Thyroidectomy</topic><topic>Thyroiditis</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Solis-Pazmino, Paola</creatorcontrib><creatorcontrib>Hallo, Alejandro</creatorcontrib><creatorcontrib>Lincango-Naranjo, Eddy</creatorcontrib><creatorcontrib>Garcia, Cristhian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>BMJ case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Solis-Pazmino, Paola</au><au>Hallo, Alejandro</au><au>Lincango-Naranjo, Eddy</au><au>Garcia, Cristhian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Black thyroid: a benign finding</atitle><jtitle>BMJ case reports</jtitle><addtitle>BMJ Case Rep</addtitle><date>2021-06-21</date><risdate>2021</risdate><volume>14</volume><issue>6</issue><spage>e242133</spage><pages>e242133-</pages><issn>1757-790X</issn><eissn>1757-790X</eissn><abstract>Physical examination revealed a hard stone consistency thyroid nodule fixed to surrounding tissues in the right lobe of approximately 15 mm. Ultrasound revealed a 17×10 mm solid nodule in the right lobe of heterogeneous echogenicity with microcalcifications. Fine-needle aspiration biopsy showed epithelial cell sheets with increased dense chromatin nuclear volume, clefts, evident nucleolus and haematic background suggestive of malignancy (Bethesda IV). [...]they do not affect the gland’s functionality.3 Black thyroids were also reported in cystic fibrosis and less common in hereditary haemochromatosis and ochronosis.4 5 Thyroid neoplasm has been reported in 65% of patients with black thyroid; nevertheless, the high prevalence of malignancy can be explained by the fact that black thyroid is diagnosed during the thyroid malignancy diagnostic workup triggered by the overdiagnosis of thyroid cancer.6 Neither black thyroid nor minocycline has been associated with an increased risk of malignancy or more aggressive cancer.7 Patient’s perspective When they found a nodule in my thyroid and explained that it could be cancer, I was devastated.</abstract><cop>England</cop><pub>BMJ Publishing Group LTD</pub><pmid>34155017</pmid><doi>10.1136/bcr-2021-242133</doi><orcidid>https://orcid.org/0000-0002-4410-7059</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Acne Antibiotics Asymptomatic Case reports Cysts Humans Images In Neuroendocrine tumors Thyroid cancer Thyroid Diseases - diagnosis Thyroid Diseases - surgery Thyroid Neoplasms - surgery Thyroidectomy Thyroiditis Tumors |
title | Black thyroid: a benign finding |
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