Clinical Implications of Colorectal Cancer Stem Cells in the Age of Single-Cell Omics and Targeted Therapies

The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor heterogeneity and suggests that within a given tumor, in analogy to normal tissues, there exists a cellular hierarchy composed of a minority of more primitive cells with enhanced longevity (ie, CSCs) that give rise to...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2021-05, Vol.160 (6), p.1947-1960
Hauptverfasser:	Frank, Markus H., Wilson, Brian J., Gold, Jason S., Frank, Natasha Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Stem Cells Colorectal Cancer Intra-Tumor Heterogeneity Omic Technologies Single-Cell Analyses Targeted Therapies
Online-Zugang:	Volltext
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