Pseudohyperaldosteroism during itraconazole treatment: a hitherto neglected clinically significant side effect

We describe a married couple who both presented with hypertension and hypokalaemia. Both patients were diagnosed with pseudohyperaldosteronism triggered by the widely used antifungal drug itraconazole. This effect appears to be dose-dependent, where a daily intake of 100 mg itraconazole is enough to...

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Veröffentlicht in:	BMJ case reports 2021-06, Vol.14 (6), p.e243191
Hauptverfasser:	Brandi, Sandra L, Feltoft, Claus L, Serup, Jørgen, Eldrup, Ebbe
Format:	Artikel
Sprache:	eng
Schlagworte:	Antifungal agents Antifungal Agents - adverse effects Blood pressure Case Report Case reports Clinical significance Dehydrogenases Drug-Related Side Effects and Adverse Reactions Enzymes Hormones Humans Hypertension Itraconazole - adverse effects Kidneys Metabolites Outpatient care facilities Patients Suffering Urine Voriconazole - adverse effects
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