Preclinical Assessment of a Novel Conformable Foam-Based Left Atrial Appendage Closure Device

Background. Left atrial appendage (LAA) occlusion has been established as an alternative to systemic anticoagulation for stroke prevention in patients with atrial fibrillation; however, limitations of current devices have slowed adoption. We present preclinical evaluations of a novel device, the Con...

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Veröffentlicht in:	BioMed research international 2021, Vol.2021, p.4556400-8
Hauptverfasser:	Sommer, Robert J., Lamport, Ronald, Melanson, David, Devellian, Carol, Levine, Andy, Cain, Christopher M., Kaplan, Aaron V., Gray, William A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Animals Anticoagulants Atrial Appendage - physiopathology Atrial Appendage - surgery Atrial fibrillation Atrial Fibrillation - physiopathology Atrial Fibrillation - surgery Blood clots Cardiac Catheterization - instrumentation Cardiac Surgical Procedures Care and treatment Catheters Clopidogrel Diagnosis Dogs Dosage and administration Echocardiography Equipment Design Evaluation Fibrillation General anesthesia In vitro methods and tests Inflammation Male Medical equipment Methods Neointima Occlusion Orifices Patients Physiological apparatus Prevention Prosthesis Design Risk factors Septal Occluder Device Silicones Stroke Stroke (Disease) Stroke - prevention & control Thrombosis Transplants & implants Treatment Outcome Tubes Venous access Water baths
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