Increased susceptibility to dextran sulfate-induced mucositis of iron-overload β-thalassemia mice, another endogenous cause of septicemia in thalassemia

Enterocyte damage and gut dysbiosis are caused by iron-overload in thalassemia (Thl), possibly making the gut vulnerable to additional injury. Hence, iron-overload in the heterozygous β-globin deficient (Hbbth3/+) mice were tested with 3% dextran sulfate solution (DSS). With 4 months of iron-gavage,...

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Veröffentlicht in:	Clinical science (1979) 2021-06, Vol.135 (12), p.1467-1486
Hauptverfasser:	Visitchanakun, Peerapat, Panpetch, Wimonrat, Saisorn, Wilasinee, Chatthanathon, Piraya, Wannigama, Dhammika Leshan, Thim-uam, Arthid, Svasti, Saovaros, Fucharoen, Suthat, Somboonna, Naraporn, Leelahavanichkul, Asada
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Death & Injury Host-Microbe Interactions Immunology & Inflammation Microbiology
Online-Zugang:	Volltext
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