SYVN1/GPX5 axis affects ischemia/reperfusion induced apoptosis of AC16 cells by regulating ROS generation

Ischemia/reperfusion (I/R) induced injury is a major cause of coronary heart disease (CHD). Increased production of reactive oxygen species (ROS) can lead to an I/R injury in CHD, and the ROS level can be regulated by Glutathione peroxidase (GPX) enzyme family. In this study, we investigated the rol...

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Veröffentlicht in:American journal of translational research 2021-01, Vol.13 (5), p.4055-4067
Hauptverfasser: Zhang, Jiehan, Jiang, Shengyang, Lu, Cheng, Pang, Jiadong, Xu, Huajie, Yang, Fenghua, Zhuang, Shaowei
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Sprache:eng
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