Neutrophils use selective autophagy receptor Sqstm1/p62 to target Staphylococcus aureus for degradation in vivo in zebrafish

Macroautophagy/autophagy functions to degrade cellular components and intracellular pathogens. Autophagy receptors, including SQSTM1/p62, target intracellular pathogens. is a significant pathogen of humans, especially in immunocompromise. may use neutrophils as a proliferative niche, but their intra...

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Veröffentlicht in:	Autophagy 2021-06, Vol.17 (6), p.1448-1457
Hauptverfasser:	Gibson, Josie F, Prajsnar, Tomasz K, Hill, Christopher J, Tooke, Amy K, Serba, Justyna J, Tonge, Rebecca D, Foster, Simon J, Grierson, Andrew J, Ingham, Philip W, Renshaw, Stephen A, Johnston, Simon A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified - metabolism Autophagy - physiology Brief Report Macrophages - metabolism Microtubule-Associated Proteins - metabolism Neutrophils - metabolism Phagosomes - metabolism Sequestosome-1 Protein - metabolism Staphylococcus aureus Zebrafish - metabolism Zebrafish Proteins - metabolism
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